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Q.

What are autoimmune diseases?

Tags: food, health, science
Asked by Neha Sahi, 12 Jan '10 12:56 pm
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Answers (3)

1.

Autoimmune disease: An illness that occurs when the body tissues are attacked by its own immune system. The immune system is a complex organization within the body that is designed normally to "seek and destroy" invaders of the body, including infectious agents. Patients with autoimmune diseases frequently have unusual antibodies circulating in their blood that target their own body tissues.

Examples of autoimmune diseases include systemic lupus erythematosus, Sjogren syndrome, Hashimoto thyroiditis, rheumatoid arthritis, juvenile (type 1) diabetes, polymyositis, scleroderma, Addison disease, vitiligo, pernicious anemia, glomerulonephritis, and pulmonary fibrosis.

Autoimmune diseases are more frequent in women than in men. It is felt that the estrogen of females may influence the immune system to predispose some women to autoimmune diseases. Furthermore, the presence of one autoimmune disease increases the chance for developing another simultaneous autoimmune disease.
Answered by Prasoon Sinha, 12 Jan '10 12:59 pm

 
  
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2.

Your body's immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. These diseases tend to run in families. Women - particularly African-American, Hispanic-American, and Native-American women - have a higher risk for some autoimmune diseases.

There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting diagnosed can be frustrating and stressful. In many people, the first symptoms are being tired, muscle aches and low fever.

The diseases may also have flare-ups, when they get worse, and remissions, when they all but disappear. The diseases do not usually go away, but symptoms can be treated.

Autoimmune disorders are diseases caused by the body producing an inappropriat ...more
Answered by gkr, 12 Jan '10 01:04 pm

 
  
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3.

Autoimmune Disease are basically development of antibodies against own body proteins. Immune System of mammals work on the basic concept of "Self" and "Non-self". Immune system develops antibodies against the "proteins" that it considers "non-self". Such proteins/ glycoproteins are known as "Antigens".

In cases of autoimmunity, the immune system starts recognizing its own proteins as "foreign particles" and starts developing antibodies against it.

The Most commonly know autoimmune disease is "Rheumatism". This is caused by Rheumatoid Factor (RF).
To cut a long story short, there are various type of antibodies including IgG (Immunoglobulin G) and IgM (Immunoglobulin M) - two major types of antibodies. RF is develoed against IgG. In simple terms, antibodies have two parts - Fc - The fixed part and FAb- the variable part that keeps on varying for different antigens/ disease factors/ proteins/ baqcteria/ viruses. RF is developed against the Fc portion and is the most commonly known ...more
Answered by manish varma, 13 Jan '10 02:15 pm

 
  
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