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Q.

Oral insulin is it reality now

Tags: reality, oral insulin
Asked by thyagarajan mahadevan, 08 May '08 04:47 pm
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Answers (3)

 
1.

oral insulin available to the liver through the ... the drug will come to the Indian market and available to them in reality.
oral insulin dosage form using any of these strategies becomes a reality
Answered by roopa vathi, 08 May '08 04:51 pm

 
  
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2.

The following companies are market leaders in the field of oral insulin:

www.generex.com Generex biotechnology have had their rapidmist delivery system (an oral insulin spray that is the flagship product of their company) approved for use in Ecuador. The liquid spray is absorbed by the buccal mucosa. They hail this system as pain free and a reality, and aim to infiltrate the European market at a later date. It is expected to begin being sold in Ecuador in early 2006.
Generex have an agreement with insulin giant Eli Lilly.

www.coremedusa.com/ - Coromed is a privately funded biotechnology company started in 1994. Their flagship product is called Alveair, and offers a needleless alternative for insulin users. The device delivers a regulated blast of insulin, and Coromed champion the fact that it has lower side-effect levels than injectable insulin.

www.nektar.com Nektar, formed from Inhale Therapeutic Systems Inc, are another company that are promising oral insulin. In col ...more
Answered by shona nair, 08 May '08 04:53 pm

 
  
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3.

Insulin is a major protein hormone secreted by the b-cells of the pancreas and is important for the control of diabetes. Insulin is usually administered to diabetic patients through subcutaneous injection. This mode of therapy has certain inherent disadvantages such as local pain, itching and insulin lipodystrophy around the injection site. Hence, pharmaceutical scientists have been trying to design an oral delivery system for insulin. Many challenges are associated with the oral delivery of insulin, relating to the physical and chemical stability of the hormone, and its absorption and metabolism in the human body. Here we discuss various strategies for the oral delivery of insulin that are being tried out, as well as methods used to improve the absorption of orally consumed insulin and to reduce its degradation by digestive enzymes.
Answered by Broken Love, 08 May '08 04:52 pm

 
  
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