It is famous for Tashkent, the capital where Indian PM Lal Bahadur Shastrit died while he had gond there to attend a peace meet with Pakistan (General Ayub Khan). It is also famous for providing a home to Zahir-ud-din Mohammad Babar, who invaded India in 1526 and founded the Mogul Dynasty in India which ruled India for almost two centuries.
Your vote on this answer has already been received
Uzbekistan is famous for its ancient cities (Bukhara, Khiva and Samarkand) which are over two and a half thousand years old. The cities were important centres of commerce and learning on a branch of the Silk Road, the trade route between China and Europe.
Over the centuries, the region known as Bactria and Sogdiana, Maverannahr, and later, \"Turkestan\", has been controlled by Persia, Alexander of Macedon, Arabs, Seljuq Turks, Mongols, Timurids, Uzbeks and Russians.