This is srinivasrao from India.i am P.hD student, i am locking to prepare the
doxofylline tablets (SR form).please provide the physical properties chemical
proprieties, half life, please provide the related article.
PLEASE GIVE ME REPLY
Thank you sir.
obstruction8. Among the physical findings, wheezing during quiet breathing11 and prolonged expiratory
time (> 5 seconds) are useful indicators of airflow limitation. These signs, however, are of no value as
guides to severity and their absence does not exclude COPD.
1. Anti-cholinergic agents
UDV 0.5mg/2mL 1 vial 3 - 4 times a day
PMDI 0.02mg/puff 2 puffs 4 times a day up to 12 puffs/day
Inhaled solution 0.025% 2 mL 3-4 times a day
Tiotropium Inhaled caps 18μg/cap 1 cap daily
2. Beta-2 agonists
Syrup 2mg/5mL 2mg to 4 mg every 6 to 8 hours
Tablet 2mg 1-2 tablets 3-4 times a day
Controlled Release tablet 4mg, 8 mg 1 tab 2 times a day
Pressurized metered dose
100μg/dose 1-2 puffs every 4 hours, may use 2
puffs prn for acute symptoms
Nebule 2.5 mg/2.5mL 2.5 mg -5 mg 3-4 times a day