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Dear sir,

This is srinivasrao from India.i am P.hD student, i am locking to prepare the
doxofylline tablets (SR form).please provide the physical properties chemical
proprieties, half life, please provide the related article.


Thank you sir.


Tags: dear sir, india, sir
Asked by srinithi srinivasarao, 28 Jan '08 10:20 am
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Answers (1)


Physical Examination. The physical examination is not a sensitive means of detecting airflow
obstruction8. Among the physical findings, wheezing during quiet breathing11 and prolonged expiratory
time (> 5 seconds) are useful indicators of airflow limitation. These signs, however, are of no value as
guides to severity and their absence does not exclude COPD.

A. Bronchodilators
1. Anti-cholinergic agents
UDV 0.5mg/2mL 1 vial 3 - 4 times a day
PMDI 0.02mg/puff 2 puffs 4 times a day up to 12 puffs/day
Ipratropium Br
Inhaled solution 0.025% 2 mL 3-4 times a day
Tiotropium Inhaled caps 18μg/cap 1 cap daily
2. Beta-2 agonists
Syrup 2mg/5mL 2mg to 4 mg every 6 to 8 hours
Tablet 2mg 1-2 tablets 3-4 times a day
Controlled Release tablet 4mg, 8 mg 1 tab 2 times a day
Pressurized metered dose
inhaler (pMDI)
100μg/dose 1-2 puffs every 4 hours, may use 2
puffs prn for acute symptoms
Salbutamol sulfate
Nebule 2.5 mg/2.5mL 2.5 mg -5 mg 3-4 times a day
Syrup ...more
Answered by Zee Viva, 28 Jan '08 10:26 am

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