Rue won critical acclaim for her television series debut, starring in the comedy Grand, before going on to work on Phenom, Minor Adjustments, Zoe, Duncan, Jack & Jane, ER, The Division and Popular.
She has appeared in several films (A Map of the World, Can't Hardly Wait, A Slipping Down Life, Gypsy 83 and had a bit part as a babysitter in Gore Verbinski's adaptation of The Ring), and so impressed director Michael Bay that a role was written into the movie Pearl Harbor for her. Rue briefly appeared in the 2006 Mike Judge film Idiocracy, in the role of the Attorney General.
She currently stars in the stage musical Little Egypt with French Stewart, Jenny O'Hara, and Gregg Henry at The Matrix Theatre in Los Angeles.
Rue guest starred in Two and a Half Men as Berta's youngest daughter Naomi who is pregnant and, as the episode progresses, eventually has her baby on Charlie's couch. Rue is currently working on the movies Man Maid and For Christ's Sake, both of which are in